2-Bromophenol

Descrição

2-Bromophenol · CAS 95-56-7 · C6H5BrO. UNII A0UB206YF0. Ponto de ebulição: 194.5; Ponto de ebulição: 194.5 °C; Ponto de fusão: 5.6.

Identificação

Descritores calculados

Propriedades físicas e químicas

Descrição física e notas de manuseio

• Yellow to red oily liquid with an unpleasant odor; mp = 6 deg C; [Merck Index] Pale yellow liquid with an odor like phenol; mp = 5 deg C; [Alfa Aesar MSDS]
• Liquid
• Yellow to red oily liquid
• Unpleasant
• Slightly soluble in chloroform; soluble in ethanol, ether, alkali
• Negative

Classificação de perigos GHS

Usos documentados

• Used as a precursor to resorcinol; [HSDB]
• Organic bromine compounds can be produced by a number of different chemical reactions; however, addition and substitution reactions are the methods most commonly employed in industrial processes. /Organic bromine compounds/
• p-Bromophenol and o-bromophenol were the major urinary phenolic bromobenzene metabolites although m-bromophenol and 4-bromocatechol were also excreted in detectable quantities. With the exception of o-bromophenol, urinary metabolites were excreted primarily as conjugates.
• Incubation of either o-bromophenol or 2-bromohydroquinone with rat liver microsomes and 0.25 mM 35S-glutathione (GSH) gave rise to several isomeric 35S-GSH conjugates. A mixture of these isomeric GSH conjugates was prepared chemically and two were purified by HPLC; 1H-NMR spectroscopy revealed that one was 2-bromo-3-(glutathion-S-yl)hydroquinone and the other was a disubstituted GSH conjugate which could be either 2-bromo-3,5-(diglutathion-S-yl)hydroquinone or 2-bromo-3,6-(diglutathion-S-yl)hydroquinone. Injection
• 4-Bromocatechol and the /o-, m- and p-/ bromophenol isomers were nephrotoxicants (measured as increased blood urea nitrogen and decreased accumulation of organic anions by renal cortical slices) but not hepatotoxicants (measured as serum glutamic pyruvate transaminase) in vivo at 0.56 mmol/kg (iv).

Sinónimos

2-BROMOPHENOL; 95-56-7; o-Bromophenol; Phenol, 2-bromo-; ortho-bromophenol; DTXSID8052641; A0UB206YF0; NSC-6970; DTXCID5031214; RefChem:85892; 202-432-7; BROMOPHENOL; 2-Bromfenol; 2-Bromo-phenol; Phenol, o-bromo-; 2-bromo phenol

Perguntas frequentes

Quais são o número CAS e a fórmula molecular de 2-Bromophenol?

CAS 95-56-7; fórmula molecular C6H5BrO; peso molecular — g/mol.

Por que outros nomes 2-Bromophenol é conhecida?

2-BROMOPHENOL, 95-56-7, o-Bromophenol, Phenol, 2-bromo-, ortho-bromophenol, DTXSID8052641.

2-Bromophenol está classificado como perigoso?

Declarações de perigo reportadas: H226, H302, H312, H315, H319.

Quais são as principais propriedades físicas de 2-Bromophenol?

Ponto de ebulição: 194.5; Ponto de ebulição: 194.5 °C; Ponto de fusão: 5.6; Ponto de fusão: 5.6 °C.

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